Breast Cancer Gene Discovered


7/15/2011 10:37:00 PM | , ,

BBC News- A gene has been known to be associated with 70% of breast cancers are difficult to treat through hormone therapy.
Study published in Nature magazine uses a new technique to test hundreds of genes at the same time, instead of one by one. Related Topics
Scientists say there are "lots of possibilities of significant influence" if the drug can be developed based on these findings.
Cancer Research UK said it would interesting to observe the follow-up study.
Hormones may promote tumor growth because that is a drug that can inhibit this process such as tamoxifen are used.
But a third of breast cancer fueled by hormones appear not to be existing drugs useless. To date only a few drugs available for patients with this type of cancer. Turn off
Researchers at the Whitehead Institute for Biomedical Research, Massachusetts, USA using the materials of small gene that turns off genes.
They injected the gene into a cancer cell to investigate and grower tumor-forming genes.
They found that the gene - PHGDH - very active, much more active than usual, at 70% of the tumors that can not be treated hormone therapy.
Identification of specific breast cancer genes is expected to be the basis of the creation of drugs that inhibit its growth.
Dr. Richard Possemato told the BBC: "There are many possible significant effect if the therapy proves effective.
"However, because we do not engage patients in research or developing chemical inhibitors that may be too early to know its influence on the general public."


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